Changes in porcine nutrient transport physiology in response to Ascaris suum infection

Koehler, Sarina; Springer, Andrea; Issel, Nicole; Klinger, Stefanie; Strube, Christina; Breves, Gerhard

doi:10.1186/s13071-021-05029-1

Parasites & Vectors

Table 8 Summary of statistical comparisons (Mann–Whitney U-tests) regarding mRNA, protein expression and functional data on 35 dpi

From: Changes in porcine nutrient transport physiology in response to Ascaris suum infection

	Single infection vs control			Trickle infection vs control
	mRNA	Protein	Ussing chamber	mRNA	Protein	Ussing chamber
35 dpi jejunum
SGLT1	U = 15, P = 0.699	U = 56, P = 0.392	ΔI_{sc glucose}: U = 8, P = 0.132	U = 7, P = 0.093	U = 1, P = 0.004	ΔI_{sc glucose}: U = 15, P = 0.699
pSGLT1	nd	U = 12, P = 0.394	J_{net glucose}: U = 6, P = 0.065	nd	U = 18, P > 0.999	J_{net glucose}: U = 7, P = 0.093
GLUT1	U = 10, P = 0.240	nd		U = 3, P = 0.015	nd
GLUT2	U = 16, P = 0.818	U = 11, P = 0.310		U = 6, P = 0.065	U = 3, P = 0.015
PepT1	U = 9, P = 0.180	U = 17, P = 0.937	ΔI_{sc gly-gln}: U = 16, P = 0.818	U = 11, P = 0.305	U = 6, P = 0.065	ΔI_{sc gly-gln}: U = 10, P = 0.240
ASCT1	nd	U = 15, P = 0.699	ΔI_{sc alanine}: U = 16, P = 0.818	nd	U = 10, P = 0.240	ΔI_{sc alanine}: U = 10, P = 0.240
Na⁺/K⁺-A	nd	U = 7, P = 0.093		nd	U = 18, P > 0.999
Hif1α	U = 9, P = 0.180	U = 14, P = 0.589		U = 7, P = 0.093	U = 9, P = 0.180
IL-4	U = 3, P = 0.015	nd		U = 15, P = 0.699	nd
IL-13	U = 6, P = 0.065	nd		U = 13, P = 0.485	nd
STAT6	U = 6, P = 0.065	nd		U = 13, P = 0.485	nd
35 dpi ileum
SGLT1	U = 13, P = 0.485	U = 9, P = 0.180	ΔI_{sc glucose}: U = 15, P = 0.699	U = 13, P = 0.485	U = 17, P = 0.937	ΔI_{sc glucose}: U = 13, P = 0.485
pSGLT1	nd	U = 13, P = 0.485	J_{net glucose}: U = 15, P = 0.699	nd	U = 16, P = 0.818	J_{net glucose}: U = 12, P = 0.394
GLUT1	U = 5, P = 0.041	nd		U = 6, P = 0.065	nd
GLUT2	U = 11, P = 0.310	U = 14, P = 0.589		U = 18, P > 0.999	U = 12, P = 0.394
PepT1	U = 9, P = 0.180	U = 4, P = 0.026	ΔI_{sc gly-gln}: U = 11, P = 0.310	U = 16, P = 0.818	U = 7, P = 0.093	ΔI_{sc gly-gln}: U = 15, P = 0.699
ASCT1	nd	nd	ΔI_{sc alanine}: U = 17, P = 0.937	nd	nd	ΔI_{sc alanine}: U = 12, P = 0.394
Na⁺/K⁺-A	nd	U = 17, P = 0.937			U = 16, P = 0.818
Hif1α	U = 7, P = 0.093	U = 2, P = 0.009		U = 15, P = 0.699	U = 3, P = 0.015
IL-4	U = 8, P = 0.132	nd		U = 0, P = 0.002	nd
IL-13	U = 16, P = 0.818	nd		U = 8, P = 0.132	nd
STAT6	U = 6, P = 0.065	nd		U = 10, P = 0.240	nd

nd not determined, Na⁺/K⁺-A Na⁺/K⁺-ATPase
Significant P-values are printed in bold

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ISSN: 1756-3305

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