Table 2 Comparison of creatinine, urinary protein/creatinine ratio, anti-L. infantum antibody titers, globulins, C-reactive protein and big endothelin-1 values of the three dogs which developed a recurrence of leishmaniasis during the trial course and were withdrawn at T90 (n = 2) and at T180 (n = 1)
Dog ID no. | T0 | T90 (dog #1, #14)/T180 (dog #2) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Creatinine (mg/dl) | UPC | L. infantum ELISA (%)a | Globulins (g/dl) | CRP (mg/dl) | Big ET-1 (pg/ml) | Creatinine (mg/dl) | UPC | L. infantum ELISA (%)a | Globulins (g/dl) | CRP (mg/dl) | Big ET-1 (pg/ml) | |
1 | 1.07 | 0.21 | Low (18.3) | 4.1 | 0.16 | 2.4 | 0.93 | 2.10 | High (30.7) | 8.6 | 7.04 | 2.8 |
2 | 0.84 | 1.27 | Medium (20.8) | 3.6 | 0.05 | 2.4 | 0.69 | 2.16 | High (34.3) | 5.4 | 0.15 | 2.4 |
14 | 0.60 | 0.41 | High (29.5) | 4.0 | 0.41 | 2.1 | 0.60 | 1.61 | Medium (23.8) | 5.1 | 1.16 | 3.6 |