Fig. 5

RH-Δompdc treatment reduced 4T1 tumor burden and improved survival of the tumor-bearing mice. a Schedule of RH-Δompdc treatment for the tumor-bearing mice. b–e Mice weight (b; n = 5), tumor weight (c; n = 4), tumor volume (d; n = 5) and survival curves (e; n = 7) of the established 4T1 tumor-bearing mice treated with RH-Δompdc tachyzoites or PBS. Results are representative of three independent experiments. The difference between groups was analyzed by two-way ANOVA with Tukey’s test (b–d), and survival data were analyzed by survival curves: log-rank (Mantel–Cox) test (e) Asterisks indicate significant difference at **P < 0.01, ***P < 0.001, **** P < 0.0001; ns, not significant. Abbreviations: i.t., intratumoral injection; s.c., subcutaneous injection