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Table 4 Predicted prevalence of anemia and its severity after 0.25 and 0.4 mg/kg primaquine

From: Model-based assessment of the safety of community interventions with primaquine in sub-Saharan Africa

Population

Dosing regimen, mg/kg

No anemia (Hb > 11–13 g/dl), %

All anemia grades (Hb < 11–13 g/dl), %

Mild anemia (Hb 7–11 to 11–13 g/dl), %

Moderate anemia (Hb 7–8 to 7–11 g/dl), %

Severe anemia (Hb < 7–8 g/dl), %

All

0

57.0

43.0

18.3

22.0

2.73

0.25

53.3

46.7

19.6

24.1

2.98

0.40

51.0

49.0

20.1

25.7

3.14

G6PD normal

0

57.4

42.6

18.2

21.7

2.73

0.25

54.1

45.9

19.3

23.7

2.95

0.40

52.0

48.0

19.8

25.1

3.09

G6PD deficient

0

50.4

49.6

19.8

27.1

2.72

0.25

40.5

59.5

24.2

31.9

3.43

0.40

34.8

65.2

25.2

36.1

3.96

  1. The definitions for anemia severity are dependent on age, sex and pregnancy status, and the complete definitions can be found in Additional file 1: Table S1