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Fig. 4 | Parasites & Vectors

Fig. 4

From: Structural changes and expression of hepatic fibrosis-related proteins in coculture of Echinococcus multilocularis protoscoleces and human hepatic stellate cells

Fig. 4

af Collagen I (Col-I) expression profile measured by western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). a Expression of Col-I assessed by WB. b At a PSC:HSC-LX2 ratio of 1:200, Col-I expression had significantly increased by days 2 and 3 but not by day 1. c Col-I expression at a PSC:HSC-LX2 ratio of 2:200 was significantly higher on days 1, 2 and 3 compared to the control. d At a PSC:HSC-LX2 ratio of 3:200, Col-I expression had increased by days 1 and 2, but decreased by day 3. e Col-I expression increased in HSCs cocultured with PSCs for 48 h. f By day 3, Col-I expression had increased at a PSC:HSC-LX2 ratio of 1:200 but had started to decrease at PSC:HSC-LX2 ratios of 2:200 and 3:200. For other abbreviations, see Fig. 1

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