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Table 2 Univariate associations with IgG1 and IgG serology

From: Assessing antibody decline after chemotherapy of early chronic Chagas disease patients

ELISA antigen Category Categories N IgG Pre-treatment IgG Post-treatment IgG1 Pre-treatment IgG1 Post-treatment
     Mean absorbance value t-test
P-value
Mean absorbance value t-test
P-value
Mean absorbance value t-test
P-value
Mean absorbance value t-test
P-value
Lysate Ethnic group Creole 30 1.120 0.355 0.650 0.364 0.599 0.045* 0.244 0.529
Qom 28 0.950 0.541 0.980 0.307
Completed treatment Yes 58 1.038 0.540 0.597 0.209 0.783 0.079 0.274 0.013*
No 13 1.159 0.778 1.180 0.589
Pre-treatment kDNA-PCR result Positive 24 1.270 0.092 0.676 0.019* 0.910 0.156 0.121 0.281
Negative 10 0.854 0.315 0.557 0.267
TSSApep-II/V/VI Ethnic group Creole 26 0.700 0.030* 0.111 0.584 0.593 0.256 0.033 0.682
Qom 27 0.321 0.091 0.327 0.046
Completed treatment Yes 53 0.507 0.049* 0.101  < 0.0001*** 0.478 0.660 0.038 0.261
No 13 0.964 0.478 0.336 0.081
Pre-treatment kDNA-PCR result Positive 21 0.738 0.640 0.105 0.996 0.591 0.194 0.0233 0.429
Negative 9 0.592 0.105 0.172 0.012
  1. Unpaired t-test P values are shown
  2. *P ≤ 0.05, **P < 0.01, ***P < 0.001