Fig. 3

Leishmania (Viannia) guyanensis strains derived from patients with treatment failure exhibited higher growth than cure-derived strains, but only under drug pressure. According to the growth parameters, differences between cure and failure groups are shown as the maximum growth time in hours (a) and the maximum number of cells (b). Bars represent means, black circles represent the average of three biological replicates from isolates within the cure group, and white circles indicate the failure group. The values for the growth curves under 8 µM Sb(III) supplementation are indicated in the graph. Multiple t-tests were conducted for the cure and failure group comparisons [with or without Sb(III)]. *P < 0.05