Fig. 5
From: Zika virus and temperature modulate Elizabethkingia anophelis in Aedes albopictus
In vitro analysis of the E. anophelis aegypti specificity and spectrum of its antiviral effect. a Sequential inoculation of Vero cells with E. anophelis aegypti for 24 h prior to infection with ZIKV, CHIKV, or DENV resulted in attenuated viral replication of ZIKV (P < 0.0001), CHIKV (P < 0.0001), and DENV (P < 0.0001). b Sequential inoculation of Vero cells with E. coli and virus did not attenuate viral replication of ZIKV (P = 0.9867), CHIKV (P > 0.9999), or DENV (P > 0.9999), demonstrating the specificity of E. anophelis aegypti as an antiviral. b Upon co-inoculating Vero cells with ZIKV and E. anophelis aegypti/E. coli, the antiviral effect was no longer present [ZIKV/E. anophelis aegypti (P = 0.6433); ZIKV/E. coli (P = 0.9987)