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Table 3 Genotypic and allelic frequencies of Kdr L1014F and Ace-1R G119S gene mutations between infected and uninfected Anopheles gambiae and Anopheles coluzzii

From: Evaluation of the interaction between insecticide resistance-associated genes and malaria transmission in Anopheles gambiae sensu lato in central Côte d’Ivoire

Species Study arm SNP/status n Genotypic frequencies [x (%)] Allelic frequencies [y (%)] OR (95% CI)
RR RS SS R S
   Kdr L1014F        
An. coluzzii Control Infected 213 102 (47.89) 96 (45.07) 15 (7.04) 300 (70.42) 126 (29.58) 1
Uninfected 208 102 (49.04) 86 (41.35) 20 (9.62) 290 (69.71) 126 (30.29) 1.03 (0.76–1.38)
SET Infected 92 40 (43.48) 46 (50.00) 6 (6.52) 126 (68.48) 58 (31.52) 1
Uninfected 118 60 (50.85) 43 (36.44) 15 (12.71) 163 (69.07) 73 (30.93) 0.97 (0.62–1.5)
An. gambiae Control Infected 187 183 (97.86) 3 (1.60) 1 (0.53) 369 (98.66) 5 (1.35) 1
Uninfected 208 207 (99.52) 1 (0.47) 0 (0) 415 (99.76) 1 (0.24) 0.17 (0.003–1.6)
SET Infected 119 117 (98.32) 2 (1.68) 0 (0) 236 (99.16) 2 (0.84) 1
Uninfected 110 109 (99.1) 1 (0.9) 0 (0) 219 (99.55) 1 (0.45) 0.53 (0.009–10.4)
   Ace-1RG119S        
An. coluzzii Control Infected 213 4 (1.88) 23 (10.80) 186 (87.32) 31 (7.28) 395 (92.72) 1
Uninfected 207 8 (3.86) 29 (14.01) 170 (82.13) 45 (10.87) 369 (89.13) 0.64 (0.38–1.06)
SET Infected 92 0 (0) 9 (9.78) 83 (90.22) 9 (4.89) 175 (95.11) 1
Uninfected 118 2 (1.69) 15 (12.71) 15 (85.60) 19 (8.05) 217 (91.95) 0.58 (0.22–1.40)
An. gambiae Control Infected 186 15 (8.06) 42 (22.58) 129 (69.35) 72 (19.32) 300 (80.64) 1
Uninfected 208 21 (10.10) 52 (25.00) 135 (64.90) 94 (22.60) 322 (77.40) 0.82 (0.57–1.17)
SET Infected 119 7 (5.88) 25 (21.01) 87 (73.11) 39 (16.39) 199 (83.61) 1
Uninfected 109 9 (8.26) 19 (17.43) 81 (74.31) 37 (16.97) 181 (83.03) 0.95 (0.56–1.62)
  1. For the genotypic frequency distribution, values between infected and uninfected groups did not differ significantly (p > 0.05). For abbreviations, see Tables 1 and 2