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Fig. 4 | Parasites & Vectors

Fig. 4

From: Genetic diversity and immunogenicity of the merozoite surface protein 1 C-terminal 19-kDa fragment of Plasmodium ovale imported from Africa into China

Fig. 4

ae Immune responses in mice immunized with rPoMSP119-GST. a Sera from immunized mice were multiply diluted (from 1:10,000 to 1:5,120,000), and the data are expressed as average optical density (OD) values. b Increasing trend of immunoglobulin G (IgG) levels detected using ELISA. c Specific immune responses in sera from mice immunized with different proteins confirmed by testing the interaction between antibodies and rPocMSP119-GST, rPowMSP119-GST and GST. The mean OD shows the strength of specific immune responses. d Avidity indices of anti-rPoMSP119-GST IgG determined by ELISA. e Splenocytes from immunized mice were stimulated with recombinant proteins, and concanavalin A (ConA) was used as a positive control. * P < 0.05, ** P < 0.01, *** P < 0.001; not significant (ns) P > 0.05. For other abbreviations, see Figs. 1 and 2

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