Study | Treatment | Dosage (µg/kg) | Day of inoculationa | Days of treatment | Preventive efficacy (%) | References |
---|---|---|---|---|---|---|
1 | Placebo | 0 | −30 | 0, 30, 60, 90, 120, 150 | – | [50] |
Simparica Trio (moxidectin) | Min. 24 | −30 | 0, 30, 60, 90, 120, 150 | 97.2 | [50] | |
Heartgard Plus (ivermectin) | Min. 6 | −30 | 0, 30, 60, 90, 120, 150 | 8.5 | [50] | |
Interceptor Plus (milbemycin oxime) | Min. 500 | −30 | 0, 30, 60, 90, 120, 150 | 35.9 | [50] | |
2 | Placebo | 0 | −30 | 0, 30, 60, 90, 120, 150 | – | [49] |
Moxidectin | 24 | −30 | 0, 30, 60, 90 | 96.8 | [49] | |
Moxidectin | 24 | −30 | 0, 30, 60, 90, 120, 150 | 96.1 | [49] | |
Heartgard Plus (ivermectin) | Min. 6 | −30 | 0, 30, 60, 90, 120, 150 | 18.7 | [49] | |
Interceptor Plus (milbemycin oxime) | Min. 500 | −30 | 0, 30, 60, 90, 120, 150 | 21.2 | [49] |