Fig. 1

The distribution of aminoacyl-tRNA synthetases (aaRSs) in the studied mosquito species. aaRSs from Anopheles (An. culicifacies, An. stephensi, An. minimus, and An. gambiae) and Ae. aegypti were characterized based on topologies and subcellular location. a Class I and II annotation was performed based on the topologies of the central catalytic domain (CCD) and the mode of substrate binding. The number of aaRSs annotated for each studied species and their localization for class I, class II, and bifunctional aaRSs is shown, with exceptions listed in brackets. For class I aaRSs, An. gambiae, An. stephensii, and An. minimus carry nine cytoplasmic and nine mitochondrial aaRSs, whereas An. culicifacies and Ae. aegypti have 10 cytoplasmic and eight mitochondrial aaRSs. b The tentative distribution of the predicted subcellular localizations (cytoplasmic and mitochondrial) for the studied An. culicifacies, An. stephensi, An. minimus, An. gambiae, and Ae. aegypti is shown