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Fig. 10 | Parasites & Vectors

Fig. 10

From: In vitro characterization of Haemonchus contortus trehalose-6-phosphate phosphatase and its immunomodulatory effects on peripheral blood mononuclear cells (PBMCs)

Fig. 10

Effect of rHcGOB protein on the transcription and secretion of Th1-, Th2-, and Th17-related cytokines in PBMCs. Cells were incubated with different concentrations of rHcGOB protein and with PBS (control) for 24 h at 37 °C and 5% CO2. a Transcription analysis of INF-γ, IL-2, IL-4, IL-17 in goat PBMCs. b The expression of IL-4 and IL-17A was detected by western blot. The results presented here are representative of three independent experiments. Asterisks indicate significant differences at **P < 0.01, and ****P < 0.0001 versus the control group. Abbreviations: Th, T-helper cells

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