Drug | Effect on L3 (% dead after 72 h), [SD (%)] at 100 µM | Effect on adult worms (% dead after 72 h), [SD (%)] at 10 µM | Drug indicationd |
---|---|---|---|
Aconitine | 88.1 (7.5) | 17.4 (5.1) | Anesthetic (gastric), antipyretic, and cardiotoxin |
Acriflavinium HCl | 79.4 (7.7) | 97.7 (2.3) | Anti-infective, intercalating agent |
Amantadine HCl | 75.5 (8.2) | 24.1 (4.0) | Antiviral, antiparkinsonian; treatment of drug-induced extrapyramidal reactions |
Aminohippuric acid | 84.8 (6.3) | 32.7 (10.2) | Renal function diagnosis |
Benzethonium chloride | 100.0 (0) | 100.0 (0) | Anti-infective (topical) |
Bitoscanate | 100.0 (0) | 16.5 (6.4) | Anthelmintic |
Brinzolamide | 82.7 (4.0) | 20.1 (11.4) | Antiglaucoma |
Captamine | 91.0 (4.6) | 35.1 (9.9) | Depigmenting agent |
Cetylpyridinium chloride | 100.0 (0) | 100.0 (0) | Anti-infective (topical) |
Ceftriaxone sodium trihydrate | 100.0 (0) | 20.6 (11.9) | Antibacterial |
Cetrimonium bromide | 100.0 (0) | 77.3 (11.4) | Anti-infective |
Chlormidazole | 93.3 (5.1) | 88.6 (11.4) | Antifungal |
Chloroxylenol | 88.3 (2.2) | 64.6 (35.4) | Antibacterial, topical, and urinary antiseptic |
Chlorpyrifos | 100.0 (0) | 73.1 (18.8) | Insecticide |
Cinnarizine | 94.7 (1.0) | 59.6 (40.06) | H1 antihistamine |
Coumaphos | 100.0 (0) | 100.0 (0) | Insecticide, cholinesterase inhibitor |
Cyproheptadine HCl | 100.0 (0) | 31.3 (3.7) | H1-antihistamine, antipruritic |
Dactinomycin | 71.4 (6.4) | 41.7 (10.4) | Antineoplastic, intercalating agent |
Debrisoquin sulfate | 91.3 (1.5) | 8.85 (1.3) | Anti-hypertensive |
Demeclocycline HCl | 81.5 (4.0) | – | Antibacterial |
Dyclonine HCl | 100.0 (0) | 29.6 (9.5) | Anesthetic (topical) |
Dibenzothiophene | 90.8 (2.8) | 13.2 (6.9) | Keratolytic |
Dimpylate | 100.0 (0) | 85.6 (15.0) | Insecticide, cholinesterase inhibitor |
Ebselen | 96.6 (1.9) | 52.5 (13.4) | Antioxidant, lipoxygenase inhibitor, inhibits oxidation of LDL |
Edoxudine | 89.8 (3.7) | 27.2 (7.1) | Antiviral |
Enilconazole sulfate | 71.0 (7.9) | 21.9 (3.1) | Antifungal |
Enoxacin | 85.4 (2.9) | 44.6 (9.6) | Antibacterial |
Ethisterone | 100.0 (0) | 52.4 (24.6) | Progestogen |
Fenthion | 100.0 (0) | 87.0 (11.3) | Insecticide, ectoparasiticide |
Floxuridine | 88.9 (2.1) | 62.6 (37.5) | Antineoplastic, antimetabolite |
Gallamine triethiodide | 88.5 (2.9) | 43.1 (11.3) | Muscle relaxant (skeletal) |
Gentian violet | 100.0 (0) | 100.0 (0) | Antibacterial, anthelmintic |
Gramicidinb | 72.7 (2.0) | 32.9 (10.1) | Antibacterial |
Halcinonide | 96.1 (0.9) | 38.7 (4.3) | Glucocorticoid, anti-inflammatory |
Hexylresorcinol | 83.6 (3.2) | 28.8 (8.7) | Anthelmintic, topical antiseptic |
Hycanthone | 78.0 (15.0) | 29.3 (13.5) | Anthelmintic, hepatotoxic |
Hydrocortisone butyrate | 77. 8 (4.0) | 54.3 (20.4) | Glucocorticoid, anti-inflammatory |
Imiquimod HCl | 80.6 (9.2) | 64.4 (24.3) | Immunomodulator |
Indapamide | 70.1 (6.0) | 36.6 (16.5) | Diuretic, antihypertensive |
Inositol | 75.9 (4.1) | 28.9 (8.9) | Growth factor |
Iodoquinol | 70.8 (5.1) | 17.9 (2.2) | Anti-amoebic |
Isoxicam | 89.5 (2.8) | 19.3 (3.6) | Anti-inflammatory |
Ivermectin | 100.0 (0) | 8.9 (1.25) | Antiparasitic |
Kanamycin A sulfate | 71.0 (3.1) | 50.9 (7.0) | Antibacterial |
Labetalol HCl | 79.9 (8.3) | 41.0 (13.2) | Adrenergic blocker |
Lasalocid sodium | 88.7 (1.6) | 10.9 (12.0) | Antibacterial |
Levamisole HCl | 93.1 (4.5) | 88.6 (11.4) | Immunomodulatory, anthelmintic |
Malathion | 100.0 (0) | – | Pediculicide, insecticide, cholinesterase inhibitor |
Megestrol acetate | 73.3 (5.54) | 51.4 (2.92) | Progestogen, antineoplastic |
Methylbenzethonium chloride | 91.5 (1.4) | 100.0 (0)c | Anti-infective |
Methylthiouracil | 100.0 (0) | 34.3 (14.2) | Antithyroid agent |
Mianserin HCl | 100.0 (0) | 19.6 (6.9) | 5HT antagonist |
Mitoxantrone HCl | 92.6 (9.8) | 39.8 (3.1) | Antineoplastic |
Morantel citrate | 100.0 (0) | 100.0 (0) | Anthelmintic |
Nadolol | 84.6 (5.8) | 52.5 (17.5) | Beta-adrenergic blocker |
Niclosamide | 76.3 (15.2) | – | Anthelmintic, teniacide |
Norethynodrel | 100.0 (0) | 36.8 (5.3) | Progestogen, in combination with estrogen as oral contraceptive |
Oxethazaine | 82.9 (6.34) | – | Anesthetic (local) |
Phenothiazine | 93.3 (0.8) | 37.1 (2.2) | Anthelmintic |
Prasterone acetate | 88.6 (7.7) | 77.1 (22.8) | Adrenocortical hormone, antidepressant |
Prednicarbate | 100.0 (0) | 29.9 (13.2) | Anti-inflammatory, glucocorticoid |
Prilocaine HCl | 88.5 (2.2) | 25.1 (5.1) | Anesthetic (local) |
Proadifen HCl | 74.9 (4.8) | 21.3 (1.2) | Cytochrome P450 inhibitor, Ca antagonist, anesthetic (local) |
Propiolactone | 92.8 (2.0) | 49.5 (4.81) | Anti-infective |
Pyrantel pamoate | 100.0 (0) | 53.0 (32.9) | Anthelmintic |
52.9 (3.9)a | |||
Selamectin | 79.9 (8.1) | – | Anthelmintic, antiparasitic, anti-mite |
Sulfanitran | 100.0 (0) | 65.7 (24.8)c | Antibacterial, coccidiostat |
Terpene hydrate | 70.5 (16.6) | 18.4 (4.5) | Expectorant |
Tetroquinone | 85.4 (4.9) | 42.9 (11.4)c | Keratolytic |
Triflupromazine HCl | 90.6 (5.6) | – | Antipsychotic |
Tylopaxol | 84.1 (8.3) | 43.8 (11.2) | Polymeric nonionic detergent |