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Table 2 IC50 values of levamisole against larval and adult S. ratti at 24, 48, and 72 h

From: Assessment of FDA-approved drugs against Strongyloides ratti in vitro and in vivo to identify potentially active drugs against strongyloidiasis

Developmental stage

Evaluation time point (h)

Concentration tested (µM)

100

10

1

0.1

IC50 value

L3

24

79.5 (8.4)

73.3 (4.5)

55.2 (25.2)

14.2 (1)

2.05

48

94 8 (2.5)

92.7 (2.9)

90.3 (3.0)

16.8 (0.7)

0.25

72

98.4 (2.8)

97.1 (2.6)

91.7 (4.4)

28.45 (2.8)

0.12

Adult

24

39.1 (2.3)

33.1 (2.1)

30.8 (1.9)

20.4 (5.6)

> 100

48

87.5 (4.5)

84.6 (2.3)

75.0 (3.1)

25.5 (0)

0.35

72

92.7 (2.2)

82.8 (1.4)

76.8 (2.3)

43.9 (3.5)

0.11