Skip to main content

Table 3 Activity of levamisole, morantel, and prasterone in the S. ratti model

From: Assessment of FDA-approved drugs against Strongyloides ratti in vitro and in vivo to identify potentially active drugs against strongyloidiasis

Treatment Dose (mg/kg) No. of rats cureda/investigated Mean adult worm burden (SD) Total adult worm burden reduction (%)
Control 1 No treatment 0/4 148 (13.0)
Control 2 No treatment 0/4 221.25 (81.5)
Control 3 No treatment 0/4 121.3 (15.4)
Levamisole 1001 4/4 0 (0) 100
102 4/4 0 (0) 100
13 4/4 68 (18.5) 43.9
Morantel 1001 3/3 0 (0) 100
102 0/4 66 (8.6) 45.2
Prasterone 1001 0/4 137 (39) 7.6
  1. Superscripts refer to the respective control batch used in the experiment