Table 3 Activity of levamisole, morantel, and prasterone in the S. ratti model
Treatment | Dose (mg/kg) | No. of rats cureda/investigated | Mean adult worm burden (SD) | Total adult worm burden reduction (%) |
|---|---|---|---|---|
Control 1 | No treatment | 0/4 | 148 (13.0) | – |
Control 2 | No treatment | 0/4 | 221.25 (81.5) | – |
Control 3 | No treatment | 0/4 | 121.3 (15.4) | – |
Levamisole | 1001 | 4/4 | 0 (0) | 100 |
102 | 4/4 | 0 (0) | 100 | |
13 | 4/4 | 68 (18.5) | 43.9 | |
Morantel | 1001 | 3/3 | 0 (0) | 100 |
102 | 0/4 | 66 (8.6) | 45.2 | |
Prasterone | 1001 | 0/4 | 137 (39) | 7.6 |