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Table 2 Major ivermectin studies carried out in cattle

From: Ivermectin as an endectocide may boost control of malaria vectors in India and contribute to elimination

Study/first author of study(year) [reference] Dosage of ivermectin Mortality of mosquitos
Fritz [29]
2009
Kenya
600 µg/kg once subcutaneously Mortality of mosquitos in 3 days post blood meal, (feeding done one day after ivermectin treatment): 100%
Controls: 10% (significance not reported)
Mortality of mosquitos in 3 days post blood meal (feeding done 13 days after ivermectin treatment): 62%
Mortality of mosquitos in 9 days post blood meal (feeding done 13 days after ivermectin treatment): 88%,
Controls: 10–38% (significance not reported)
Naz [17]
2013
Pakistan
200 µg/kg once subcutaneously An. culicifacies
Mortality of mosquito in 3 days post blood meal: 65%
Controls: 9%
Mortality of mosquito in 9 days post blood meal: 80%
Controls: 17%
An. stephensi
Mortality of mosquito in 3 days post blood meal: 80%
Controls: 10%
Mortality of mosquito in 9 days post blood meal: 80%
Controls: 25%
Pooda [30]
2015
Burkina Faso
200 µg/kg injected Reduction in mortality of mosquitos by 75% in the third week and by 45% in the fourth week post ivermectin treatment
Poche [18]
2015
Kenya
100–200 µg/kg orally Mortality of mosquito in 3 days post blood meal: 45–63%
Mortality of mosquito in 9 days post blood meal: 65–94%
Lyimo [31]
2017
Tanzania
200 µg/kg once subcutaneously Survival and fecundity of An. arabiensis were reduced by 52.5% and 64.6%, respectively
Chaccour [19]
2018
Tanzania
5 subcutaneous implants of 23 mg each, tested over 40 weeks Significant increased mortality of mosquitos in 3 days and 10 days after blood meal (significant difference)
Cramer [16]
2021
Vietnam
200 µg /kg once subcutaneously Ivermectin treatment significantly reduced survivorship of An. dirus up to 20 days and An. epiroticus up to 8 days
Makhanthisa [32]
2021
South Africa
200 µg/kg injected Significant increased mortality of mosquitos on day 7, 13 and 21 post ivermectin treatment and also lead to reduced egg production