Table 2 Major ivermectin studies carried out in cattle
Study/first author of study(year) [reference] | Dosage of ivermectin | Mortality of mosquitos |
|---|---|---|
Fritz [29] 2009 Kenya | 600 µg/kg once subcutaneously | Mortality of mosquitos in 3 days post blood meal, (feeding done one day after ivermectin treatment): 100% Controls: 10% (significance not reported) Mortality of mosquitos in 3 days post blood meal (feeding done 13 days after ivermectin treatment): 62% Mortality of mosquitos in 9 days post blood meal (feeding done 13 days after ivermectin treatment): 88%, Controls: 10–38% (significance not reported) |
Naz [17] 2013 Pakistan | 200 µg/kg once subcutaneously | An. culicifacies Mortality of mosquito in 3 days post blood meal: 65% Controls: 9% Mortality of mosquito in 9 days post blood meal: 80% Controls: 17% An. stephensi Mortality of mosquito in 3 days post blood meal: 80% Controls: 10% Mortality of mosquito in 9 days post blood meal: 80% Controls: 25% |
Pooda [30] 2015 Burkina Faso | 200 µg/kg injected | Reduction in mortality of mosquitos by 75% in the third week and by 45% in the fourth week post ivermectin treatment |
Poche [18] 2015 Kenya | 100–200 µg/kg orally | Mortality of mosquito in 3 days post blood meal: 45–63% Mortality of mosquito in 9 days post blood meal: 65–94% |
Lyimo [31] 2017 Tanzania | 200 µg/kg once subcutaneously | Survival and fecundity of An. arabiensis were reduced by 52.5% and 64.6%, respectively |
Chaccour [19] 2018 Tanzania | 5 subcutaneous implants of 23 mg each, tested over 40 weeks | Significant increased mortality of mosquitos in 3 days and 10 days after blood meal (significant difference) |
Cramer [16] 2021 Vietnam | 200 µg /kg once subcutaneously | Ivermectin treatment significantly reduced survivorship of An. dirus up to 20 days and An. epiroticus up to 8 days |
Makhanthisa [32] 2021 South Africa | 200 µg/kg injected | Significant increased mortality of mosquitos on day 7, 13 and 21 post ivermectin treatment and also lead to reduced egg production |