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Table 6 Comparison of the model performance on the train and validation set. For the computation of the sensitivity and specificity the threshold for each model for positive predictions was chosen such that the sensitivity on the training set is 95%

From: Identification of parameters and formulation of a statistical and machine learning model to identify Babesia canis infections in dogs using available ADVIA hematology analyzer data

Model

Train

Validation

 

AUC (%)

Sensitivity (%)

Specificity (%)

AUC (%)

Sensitivity (%)

Specificity (%)

Conventional statistics (rule-based)

93.7 (90.1–96.6, 95% CI)

89.7 (82.5–95.6, 95% CI)

97.7 (96.9–98.6, 95% CI)

91.1 (80.6–98.9, 95% CI)

84.6

97.7 (97.3–98.1, 95% C.I

Decision tree

97.0 (95.0–98.6, 95% CI)

95.4 (90.7–99.7, 95% CI)

89.1 (87.2–90.8, 95% CI)

98.0 (96.7–99.0, 95% CI)

100

87.0 (86.1–87.8, 95% CI)

Logistic regression

99.3 (98.8–99.7, 95% CI)

95.4 (90.5–98.9, 95% CI)

96.8 (95.6–97.7, 95% CI)

98.8 (98.3–99.2, 95% CI)

100

89.7 (88.8–90.5, 95% CI)

Random forest

99.3 (98.6–99.7, 95% CI)

95.4 (90.3–98.9, 95% CI)

96.9 (95.9–97.8, 95% CI)

99.4 (98.8–99.8, 95% CI)

100

95.7 (95.1–96.2, 95% CI)

XGBoost

99.3 (98.8–99.8, 95% CI)

95.4 (90.6–99.0, 95% CI)

96.8 (95.7–97.7, 95% CI)

99.4 (98.5–99.9, 95% CI)

100

93.7 (93.1–94.3, 95% CI)