Group | Treatment | Oral dosageb | No. of dogs | Day of L3 D. immitis inoculationa | Days of treatment | Days of blood microfilariae and adult D. immitis antigen testing | Day of necropsy and adult D. immitis worm recovery |
---|---|---|---|---|---|---|---|
T01 | Placebo control | na | 6 | -30 | 0, 30, 60, 90, 120, 150 | -63, -35, 60, 180, 210, 236 | 241 |
T02 | Simparica Trio | Label dosing | 6 | ||||
T03 | Heartgard Plus | Label dosing | 6 | ||||
T04 | Interceptor Plus | Label dosing | 6 |