Knockdown resistance (kdr) gene of Aedes aegypti in Malaysia with the discovery of a novel regional specific point mutation A1007G

Table 1 Correlation of genotype S989P with the resistance phenotype toward permethrin for the field strain Aedes aegypti

States	Location	Phenotype status	n	S989P
				Genotype			Alleles		Frequency P allele	Odd ratio (OR)	Fisher’s exact test (P value)
				S/S	S/P	P/P	TCC	CCC	Frequency P allele	Odd ratio (OR)	Fisher’s exact test (P value)
Penang	Sungai Dua (SD)	Resistant	3	0	2	1	2	4	0.667	0	0.333
	Sungai Dua (SD)	Susceptible	2	0	0	2	0	4	1	0	0.333
	Balik Pulau (BP)	Resistant	4	0	0	4	0	8	1	\(\infty\)	0.165
	Balik Pulau (BP)	Susceptible	3	1	0	2	2	4	0.667	\(\infty\)	0.165
Selangor	Alam Budiman (AB)	Resistant	4	2	2	0	6	2	0.25	\(\infty\)	0.424
	Alam Budiman (AB)	Susceptible	2	2	0	0	4	0	0	\(\infty\)	0.424
	TUDM (TDM)	Resistant	3	3	0	0	6	0	0	0	0.571
	TUDM (TDM)	Susceptible	4	3	1	0	7	1	0.125	0	0.571
Kelantan	Pauh, Panji (PNJ)	Resistant	10	10	0	0	20	0	0	N/A	0.999
	Pauh, Panji (PNJ)	Susceptible	–	–	–	–	–	–	–	N/A	0.999
	Flat Buluh Kubu (FLT)	Resistant	10	9	0	1	18	2	0.1	\(\infty\)	0.823
	Flat Buluh Kubu (FLT)	Susceptible	1	1	0	0	2	0	0	\(\infty\)	0.823

“–”: No individuals died during adult bioassay, thus the genotype and the allelic frequency cannot be determined
N/A: could not be determined because no individual died because of susceptible phenotype. \(\infty\) suggests a high risk for the association between phenotype and genotype

ISSN: 1756-3305