Knockdown resistance (kdr) gene of Aedes aegypti in Malaysia with the discovery of a novel regional specific point mutation A1007G

Table 3 Results on the association of F1534C allele with the insecticide resistance phenotype

States	Location	Phenotype status	n	F1534C
				Genotype			Alleles		Frequency C allele	Odd ratio (OR)	Fisher’s exact test (P-value)
				F/F	F/C	C/C	TTC	TGC	Frequency C allele	Odd ratio (OR)	Fisher’s exact test (P-value)
Penang	Sungai Dua (SD)	Resistant	20	7	7	6	21	19	0.475	1.069	0.999
	Sungai Dua (SD)	Susceptible	12	3	7	2	13	11	0.458	1.069	0.999
	Balik Pulau (BP)	Resistant	20	3	12	5	18	22	0.55	3.318	0.042
	Balik Pulau (BP)	Susceptible	13	8	3	2	19	7	0.269	3.318	0.042
Selangor	Alam Budiman (AB)	Resistant	20	1	15	4	17	23	0.575	\(\infty\)	0.022
	Alam Budiman (AB)	Susceptible	3	3	0	0	6	0	0	\(\infty\)	0.022
	TUDM (TDM)	Resistant	20	8	11	1	27	13	0.325	16.852	0.001
	TUDM (TDM)	Susceptible	18	17	1	0	35	1	0.028	16.852	0.001
Kelantan	Pauh, Panji (PNJ)	Resistant	20	0	1	19	1	39	0.975	N/A	0.999
	Pauh, Panji (PNJ)	Susceptible	0	–	–	–	–	–	–	N/A	0.999
	Flat Buluh Kubu (FLT)	Resistant	20	1	1	18	3	37	0.925	\(\infty\)	0.02
	Flat Buluh Kubu (FLT)	Susceptible	1	1	0	0	2	0	0	\(\infty\)	0.02

“–”: No individuals died during adult bioassay; thus, the genotype and the allelic frequency cannot be determined. N/A indicates that it could not be determined because no individual died because of susceptible phenotype. \(\infty\) suggests a high risk for the association between phenotype and genotype

ISSN: 1756-3305