Knockdown resistance (kdr) gene of Aedes aegypti in Malaysia with the discovery of a novel regional specific point mutation A1007G

Table 4 Association of potential novel mutation A1007G allele with the insecticide resistance phenotype

States	Location	Phenotype status	n	A1007G
				Genotype			Alleles		Frequency G allele	Odd ratio (OR)	Fisher’s exact test (P-value)
				A/A	A/G	G/G	GCC	GGC	Frequency G allele	Odd ratio (OR)	Fisher’s exact test (P-value)
Kelantan	Pauh, Panji (PNJ)	Resistant	10	0	3	7	3	17	0.85	N/A	0.999
	Pauh, Panji (PNJ)	Susceptible	–	–	–	–	–	–	–	N/A	0.999
	Flat Buluh Kubu (FLT)	Resistant	10	1	0	9	2	18	0.90	\(\infty\)	0.026
	Flat Buluh Kubu (FLT)	Susceptible	1	1	0	0	2	0	0	\(\infty\)	0.026

“–”: No individuals died during adult bioassay; thus, the genotype and allelic frequency cannot be determined. N/A: it could not be determined because no individual died because of susceptible phenotype. \(\infty\) suggests a high risk for the association between phenotype and genotype

ISSN: 1756-3305