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Fig. 4 | Parasites & Vectors

Fig. 4

From: Inhibition of COX-2 ameliorates murine liver schistosomiasis japonica through splenic cellular immunoregulation

Fig. 4

COX-2 inhibition decreased Sj infection-derived Th1, Th2 but not Th17 cells in the spleen. a Isolated spleen cells were stained with dead-APC-A750, CD3-PC5.5, CD4- FITC, IFN-γ-APC, IL-4-PB450, and IL-17-PC7 antibodies. IFN-γ+ CD4+ cells (Th1), IL-4+CD4+ cells (Th2), or IL-17+CD4+ cells (Th17) were analyzed and data shown are gated on CD3+CD4+ T cells. Numbers represent the percentage of the boxed population. b The expression of Th1 cells in CD3+CD4+ T cells in the spleen was evaluated. c Th2 or d Th17 cells in CD3+CD4+ T cells in spleen were evaluated. Data are expressed as the mean ± SD (Student’s t-test, statistic P-value is marked in the figures)

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