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Table 3 Assessment of hair regrowth on dogs before and after treatment for generalized demodicosis

From: Fluralaner 5.46% (w/w) flavored chewable tablet (Bravecto® 1-Month) is effective for treatment of canine generalized demodicosis

Day of study Score Body areas with hair regrowth versus pre-administration assessment Fluralaner tablets Topical imidacloprid-moxidectin
  Assessment prior to any study treatments
−2 1 Alopecia > 0 to 50% of the body 7/8 (87.5%) 7/8 (87.5%)
  2 Alopecia > 50 to ≤ 90% of the body 1/8 (12.5%) 1/8 (12.5%)
  3 Alopecia > 90% of the body 0/8 (0.0%) 0/8 (0.0%)
  Hair regrowth after treatment on days 0, 28, and 56a and on day 84
28 1  > 0 to 50% hair regrowth 2/8 (25.0%) 5/8 (62.5%)
  2  > 50 to ≤ 90% hair regrowth 4/8 (50.0%) 3/8 (37.5%)
  3  > 90% improvement 2/8 (25.0%) 0/8 (0.0%)
56 1  > 0 to 50% 0/7 (0.0%) 4/8 (50.0%)
  2  > 50 to ≤ 90% 2/7 (28.6%) 2/8 (25.0%)
  3  > 90% 5/7 (71.4%) 2/8 (25.0%)
84 1  > 0 to 50% 0/7 (0.0%) 1/8 (12.5%)
  2  > 50 to ≤ 90% 0/7 (0.0%) 2/8 (25.0%)
  3  > 90% 7/7 (100.0%) 5/8 (62.5%)
  1. aHair regrowth assessments were made before treatments were administered on days 28 and 56