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Table 1 Mortality rate (%) of snails after wettable powder of niclosamide (WPN) treatment with or without the alternative oxidase (AOX) inhibitor salicylhydroxamic acid (SHAM)

From: The identification of alternative oxidase in intermediate host snails of Schistosoma and its potential role in protecting Oncomelania hupensis against niclosamide-induced stress

Group

6 h

12 h

24 h

48 h

χ2

P

H2O

5.00 ± 7.07

3.33 ± 2.36

1.67 ± 2.36

5.33 ± 4.11

0.247

0.684

Methanol

1.67 ± 2.36

7.22 ± 6.14

2.78 ± 2.08

12.50 ± 2.50

3.761

0.056

SHAM

6.67 ± 6.24

5.00 ± 4.08

1.67 ± 2.36

12.50 ± 2.50

0.751

0.415

0.04 mg/L WPN

0.00 ± 0.00

0.00 ± 0.00

1.25 ± 2.17

10.89 ± 11.69 a, b

14.656

0.000

0.06 mg/L WPN

1.25 ± 2.17

1.25 ± 2.17

8.75 ± 4.15

32.50 ± 10.90* a, b, c

40.815

0.000

0.08 mg/L WPN

2.50 ± 2.50

2.50 ± 2.50

18.57 ± 7.49* a, b

60.24 ± 13.12* a, b, c

88.298

0.000

0.1 mg/L WPN

5.24 ± 0.34

32.21 ± 12.66* a

49.58 ± 9.60* a

91.67 ± 8.03* a, b, c

144.024

0.000

0.04 mg/L WPN + SHAM

0.00 ± 0.00

3.67 ± 2.62 d

34.90 ± 3.74* a, b

91.72 ± 6.02* a, b, c

216.473

0.000

0.06 mg/L WPN + SHAM

2.50 ± 2.50

7.32 ± 4.02 d

77.50 ± 5.59* a, b, d

95.00 ± 3.54* a, b, c

194.708

0.000

0.08 mg/L WPN + SHAM

11.25 ± 4.15

34.29 ± 12.05* a

82.50 ± 5.59* a, b, d

100.00 ± 0.00* a, b, c, d

161.253

0.000

0.1 mg/L WPN + SHAM

19.29 ± 3.75* d

46.68 ± 6.74* ad

87.32 ± 9.17* a, b, d

100.00 ± 0.00* a, b, c, d

189.074

0.000

  1. Lowercase letters indicate the following: a, mortality at that time point was significantly higher than that at 6 h for the same group (P < 0.05); b, mortality at that time point was significantly higher than that at 12 h for the same group (P < 0.05); c, mortality at that time point was significantly higher than that at 24 h, for the same group (P < 0.05); d, significant difference in mortality between the treatment group and the 0.1 WPN group at that time point (P < 0.05)
  2. * P < 0.05 (significant difference in mortality between that treatment group and the H2O group at that time point)