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Table 8 Randomised controlled trial studies included in systematic review

From: Systematic review to evaluate a potential association between helminth infection and physical stunting in children

Authors Year Country Helminth type Population of interest ROB—overall grade Association found between helminth infection and stunting?
Assis et al. 1998 Brazil schisto SAC Low No
Beach et al. 1999 Haiti STHs SAC Low No
Greenberg et al. 1981 Bangladesh STHs PSAC + SAC Low No
Gupta et al. 1982 Guatemala STHs PSAC Low No
Lai et al. 1995 Malaysia STHs SAC Low No
Larocque et al. 2006 Peru STHs PW Low Possibly
Liu et al. 2017 China STHs SAC Low No
McGarvey et al. 1996 Philippines schisto PSAC + SAC Low No
KF Michaelsen. 1985 Botswana STHs SAC Low No
Mofid et al. 2017 Peru STHs BFW Low Possibly
Ndibazza et al. 2010 Uganda STHs + schisto PW Low Possibly
Nga et al. 2011 Vietnam STHs SAC Low No
Northrop-Clewes et al. 2001 Bangladesh STHs PSAC Low No
Rousham et al. 1994 Bangladesh STHs PSAC + SAC Low No
Stoltzfus et al. 2004 Tanzania STHs PSAC + SAC Low No
Taylor et al. 2001 South Africa STHs + schisto SAC Low No
Watkins & Pollitt 1996 Guatemala STHs SAC Low No
Willett et al. 1979 Tanzania STHs PSAC + SAC Low No
Yap et al. 2014 China STHs SAC Low No
Akpan et al. 2018 Nigeria STH's PW Low No
Awasthi et al. 2000 India STHs PSAC Medium No
Befidi-Mengue et al. 1992 Cameroon schisto + STHs SAC Medium No
Donnen et al. 1998 Democratic Republic of the Congo STHs I Medium No
Dossa et al. 2001 Benin STHs PSAC Medium No
Garg et al. 2002 Kenya STHs PSAC Medium Possibly
Goto et al. 2009 Bangladesh STHs I Medium No
Hadju et al. 1997 Indonesia STHs SAC Medium Yes
Hlaing 1994 Myanmar STHs PSAC + SAC Medium Possibly
Jinabhai et al. 2001a South Africa STHs + schisto SAC Medium No
Jinabhai et al. 2001b South Africa STHs + schisto SAC Medium No
Joseph et al. 2015 Peru STHs I Medium No
Kruger et al. 1996 South Africa STHs SAC Medium No
Nokes et al. 1999 China STHs + schisto SAC Medium No
Ostwald et al. 1984 Papua New Guinea STHs SAC Medium No
Sarkar et al. 2002 Bangladesh STHs PSAC + SAC Medium No
Satya Deepti et al. 2015 India STHs PW Medium No
Simeon et al. 1995 Jamaica STHs SAC Medium No
Stephenson et al. 1985 Kenya STHs + schisto SAC Medium No
Stephenson et al. 1989a Kenya STHs SAC Medium Yes
Stephenson et al. 1993 Kenya STHs SAC Medium Yes
Stoltzfus et al. 1997 Tanzania STHs SAC Medium Yes
Tee et al. 2013 Malaysia STHs SAC Medium No
Thein et al. 1991 Myanmar STHs SAC Medium Possibly
  1. BFW: breast-feeding women, I: infants (0-1 year old), Possibly: some association between helminth infection and stunting may have been found, or a suggestion of benefit with anthelmintic treatment, but no statistically significant association was found. Also applies when a suspected association was found in case reports and case series, as these study designs provide a weaker level of evidence. (Age group category thresholds for children as defined by WHO [16]), PSAC: pre-school age children (1-5 year olds), PW: pregnant women, ROB: risk of bias, SAC: school age children (5+ to 20 year olds), schisto: schistosomes, STH: soil-transmitted helminths