Fig. 3

Reduction of B7-H4 on mouse dDCs cells by T. gondii infection related to the expression of MHC-II and co-stimulatory molecules CD80 and CD86. a Flow cytometry analyses of CD80, CD86, MHC-II, and B7-H4 levels in CD11c⁺CD8a⁻ and CD11c⁺CD8a⁺ dDCs from WT uninfected, WT infected, and B7-H4^−/− infected groups of pregnant female mice. b–d Histogram analysis of CD80, CD86, MHC-II, and B7-H4 expression changes in CD11c⁺CD8a⁻ and CD11c⁺CD8a⁺ dDCs from WT uninfected, WT infected, and B7-H4^−/− infected pregnant female mice. Data shown are means ± SD. At least eight pregnant female mice per group were assayed individually by unpaired t-test; uninfected vs infected group, infected vs B7-H4^−/− infected group