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Fig. 3 | Parasites & Vectors

Fig. 3

From: B7-H4 reduction induced by Toxoplasma gondii infection results in dysfunction of decidual dendritic cells by regulating the JAK2/STAT3 pathway

Fig. 3

Reduction of B7-H4 on mouse dDCs cells by T. gondii infection related to the expression of MHC-II and co-stimulatory molecules CD80 and CD86. a Flow cytometry analyses of CD80, CD86, MHC-II, and B7-H4 levels in CD11c+CD8a and CD11c+CD8a+ dDCs from WT uninfected, WT infected, and B7-H4−/− infected groups of pregnant female mice. bd Histogram analysis of CD80, CD86, MHC-II, and B7-H4 expression changes in CD11c+CD8a and CD11c+CD8a+ dDCs from WT uninfected, WT infected, and B7-H4−/− infected pregnant female mice. Data shown are means ± SD. At least eight pregnant female mice per group were assayed individually by unpaired t-test; uninfected vs infected group, infected vs B7-H4−/− infected group

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