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Table 2 Baseline characteristics of patients and verification indices

From: Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

Total number of population = 30

Control group

C. sinensis group

P-value

Sex, n (%)

 Male

5 (62.5)

13 (59.1)

 

 Female

3 (37.5)

9 (40.9)

 

Age (years)

45.5 (24–65)

47.0 (36–68)

0.26

ALB (g/l)

43.8 ± 4.6

46.8 ± 4.5

0.12

UA (μmol/l)

268.1 ± 92.4

343.1 ± 152.4

0.20

Harmful alcohol intake*

0

0

 

Biochemical indices

 TBA (μmol/l)

3.6 ± 2.0

3.6 ± 1.9

0.96

 ALT (IU/l)

18.1 ± 8.0

27.8 ± 10.7

0.03

 AST (IU/l)

16.1 ± 3.8

27.4 ± 8.3

0.001

 GGT (IU/l)

18.4 ± 2.3

29.6 ± 6.6

 < 0.000

 HDL (mmol/l)

1.3 ± 0.2

1.1 ± 0.3

0.05

 CHE (IU/l)

7945.0 ± 1597.2

8613.1 ± 1804.2

0.36

Metabolites

 l-pipecolic acid (ng/ml)

225.6 ± 30.8

940.3 ± 213.3

0.003

 Hypoxanthine (ng/ml)

5279.8 ± 578.6

9963.7 ± 761.0

 < 0.000

 d-glucuronate (ng/ml)

149.9 ± 7.5

339.3 ± 24.7

 < 0.000

 3-methylglutaric acid (ng/ml)

32.6 ± 4.1

58.5 ± 12.9

0.07

 Glycodeoxycholic acid (ng/ml)

298.9 ± 96.2

363.7 ± 82.3

0.62

 Xanthine (ng/ml)

593.3 ± 46.3

622.8 ± 31.3

0.61

  1. Numerical variables are shown as median (range) or mean ± SEM
  2. Categorical variables are expressed n (%)
  3. ALB albumin, UA Uric acid, TBA total bile acid, ALT alanine aminotransferase, AST aspartate transaminase, GGT glutamyl transpeptidase, HDL high density lipoprotein, CHE cholinesterase
  4. *Harmful alcohol intake: > 20 g in women and > 30 g in men