Fig. 8

Characteristics of the TGF-β signaling pathway in BALB/c mice infected with P.y17XL. a ELISA was performed to detect the levels of TGF-β in the supernatants of cultured spleen cells in BALB/c mice infected with P.y17XL. b TGF-β1,Smad2/3 and p-Smad2/3 protein expression levels in BALB/c mice infected with P.y17XL. The results of three independent repeats are shown. Data are presented as the mean ± SD. Asterisks indicate significant difference at *P < 0.05 and **P < 0.01 vs. baseline levels. Abbreviations: ELISA, Enzyme-linked immunosorbent assay; p-, phosphorylated; TGF-β, transforming growth factor beta