Fig. 2

A Schematic diagram of 3D imaging of cell-to-cell interactions using a holotomographic microscope. B The 3D images of pseudo-colored cells along the X–Y, X–Z and Y–Z planes are shown in the panels from left to right. Arrowheads, lipid droplet-like dots. C X–Y view of the B. mandrillaris trophozoites interacting with human neuroblastoma SH-SY5Y cells (left panel), and the cytoplasmic bridge (arrows in the middle and right panel) in the Y–Z plane. D The snapshot image of a rotating trophozoite shows anchoring sites (arrows in the left, middle and right panels). Abbreviations: B.M., B. mandrillaris; SH-SY5Y, human neuroblastoma cell line