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Table 2 Pharmacokinetic parameters of fluazuron following orally administration of fluazuron (10 mg/kg) to guinea pigs (n = 8)

From: Fluazuron orally administered to guinea pigs: pharmacokinetic and efficacy against Amblyomma sculptum

Pharmacokinetic parameters

Arithmetic mean ± SD

Cmax (ng/ml)

356.55 ± 133.75

tmax (d)

0.77 ± 0.35

AUC0-t (ng.d/ml)

2327.99 ± 673.39

AUC0-∞ (ng.d/ml)

2768.13 ± 708.61

t½ (d)

6.94 ± 1.47

  1. tmax time to reach peak plasma concentration, Cmax peak plasma concentration, AUC area under the (zero moment) curve from time 0 to the last detectable concentration, t1/2 terminal half-life, AUC area under the (zero moment) curve from time 0 to infinity
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Parasites & Vectors

ISSN: 1756-3305

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