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Table 2 Pharmacokinetic parameters of fluazuron following orally administration of fluazuron (10 mg/kg) to guinea pigs (n = 8)

From: Fluazuron orally administered to guinea pigs: pharmacokinetic and efficacy against Amblyomma sculptum

Pharmacokinetic parameters Arithmetic mean ± SD
Cmax (ng/ml) 356.55 ± 133.75
tmax (d) 0.77 ± 0.35
AUC0-t (ng.d/ml) 2327.99 ± 673.39
AUC0-∞ (ng.d/ml) 2768.13 ± 708.61
t½ (d) 6.94 ± 1.47
  1. tmax time to reach peak plasma concentration, Cmax peak plasma concentration, AUC area under the (zero moment) curve from time 0 to the last detectable concentration, t1/2 terminal half-life, AUC area under the (zero moment) curve from time 0 to infinity
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Parasites & Vectors

ISSN: 1756-3305

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