Fluazuron orally administered to guinea pigs: pharmacokinetic and efficacy against Amblyomma sculptum

Parasites & Vectors

Table 3 Evaluation of detached and molting process of engorged larvae of Amblyomma sculptum recovered from artificially infested guinea pigs for control and fluazuron treated groups (at 1, 5 and 10 mg/kg)

Group	N of engorged larvae detached	Larvicidal efficacy (%)	N of nymphs that have molted	Nymphs that have molted (%)	Molting process inhibition (%)
CG	266.8¹ ± 54.6^a*	–	247.0¹ ± 55.1	92.4¹ ± 7.0^a	–
	(189–359)²	–	(176–330)²	(77.5–99.2)²	–
G1	419.2¹ ± 276.0^a**	0	0¹	0^{1, b}	100
	(132–777)²	0	(0)²	(0)²	100
G2	427.2¹ ± 244.6^a**	0	0¹	0^{1, b}	100
	(227–788)²	0	(0) ²	(0)²	100
G3	371.3¹ ± 203.1^a**	0	0¹	0^{1, b}	100
	(101–598)²	0	(0) ²	(0)^{1, 2}	100

^aIn column of engorged lavae detached the groups do not differ from each other (p=0.8123) and in the column of nymphs that have molted (%) the control group differ from the treated groups (p<0.0001)
^bn column of nymphs that have molted (%) the treated groups do not differ from each other
CG Control group, G1 1 mg/kg, G2 5 mg/kg, G3 10 mg/kg
^*Normal morphology and behavior
^**Engorged larvae shriveled and darker
¹Arithmetic mean
²Minimum and maximum values

ISSN: 1756-3305