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Table 2 Diagnostic accuracy of the three serological tests, using Bayesian latent class models with non- informative prior distributions, except to prevalence values, for Portuguese and Brazilian dogs, given by posterior median and 95% credibility intervals

From: Leishmania exposure in dogs from two endemic countries from New and Old Worlds (Brazil and Portugal): evaluation of three serological tests using Bayesian Latent Class Models

  Prevalence median (95% CI) Serological tests Sensitivity median (95% CI) Specificity median (95% CI) PPV median (95% CI) NPV median (95% CI)
Portuguese dog population   Leishmania infantum IgG ELISA® 88.5 (72.5–97.3) 92.5 (88.0–95.9) 64.4 (47.1–79.1) 98.2 (95.1–99.6)
13.4 (9.0–18.7) EIE-LVC® 85.2 (67.7–95.7) 99.1 (96.8–99.9) 93.3 (78.4–99.4) 97.8 (94.6–99.4)
  DPP-LVC® 96.6 (83.1–99.9) 99.1 (96.6–100.0) 94.3 (79.5–99.7) 99.5 (97.2–100.0)
Brazilian dog population   Leishmania infantum IgG ELISA® 79.9 (61.3–95.9) 98.7 (95.1–99.9) 94.5 (79.3–99.7) 94.7 (88.3–99.1)
21.6 (15.0–28.3) EIE-LVC® 88.2 (73.7–97.0) 81.8 (74.3–88.1) 56.9 (41.5–71.1) 96.3 (90.6–99.1)
  DPP-LVC® 85.7 (70.7–96.0) 90.7 (84.3–95.7) 71.6 (53.7–86.7) 95.9 (90.6–99.0)
  1. Deviance information criterion: 69.96; pD = 10.07
  2. Prior information for prevalence: uniform (0, 0.30)
  3. CI credibility intervals, IgG immunoglobulin G, ELISA enzyme-linked immunosorbent assay, EIE-LVC® ELISA canine visceral leishmaniosis test, DPP-LVC® Dual Path Platform canine visceral leishmaniosis test, PPV positive predictive value, NPV negative predictive value