Table 2 Diagnostic accuracy of the three serological tests, using Bayesian latent class models with non- informative prior distributions, except to prevalence values, for Portuguese and Brazilian dogs, given by posterior median and 95% credibility intervals
Prevalence median (95% CI) | Serological tests | Sensitivity median (95% CI) | Specificity median (95% CI) | PPV median (95% CI) | NPV median (95% CI) | |
|---|---|---|---|---|---|---|
Portuguese dog population | Leishmania infantum IgG ELISA® | 88.5 (72.5–97.3) | 92.5 (88.0–95.9) | 64.4 (47.1–79.1) | 98.2 (95.1–99.6) | |
13.4 (9.0–18.7) | EIE-LVC® | 85.2 (67.7–95.7) | 99.1 (96.8–99.9) | 93.3 (78.4–99.4) | 97.8 (94.6–99.4) | |
DPP-LVC® | 96.6 (83.1–99.9) | 99.1 (96.6–100.0) | 94.3 (79.5–99.7) | 99.5 (97.2–100.0) | ||
Brazilian dog population | Leishmania infantum IgG ELISA® | 79.9 (61.3–95.9) | 98.7 (95.1–99.9) | 94.5 (79.3–99.7) | 94.7 (88.3–99.1) | |
21.6 (15.0–28.3) | EIE-LVC® | 88.2 (73.7–97.0) | 81.8 (74.3–88.1) | 56.9 (41.5–71.1) | 96.3 (90.6–99.1) | |
DPP-LVC® | 85.7 (70.7–96.0) | 90.7 (84.3–95.7) | 71.6 (53.7–86.7) | 95.9 (90.6–99.0) |