| WT | PbBrca2-KO1 | PbBrca2-KO3 |
---|
Ring | 243 (60.75 ± 21.23) | 357 (71.4 ± 15.82) | ** | ▲ | 264 (52.8 ± 24.67) | ** | ▲ |
Trophozoite | 104 (26 ± 6.98) | 34 (6.8 ± 2.68) | ** | ▽ | 63 (12.6 ± 10.92) | ** | ▽ |
Schizont | 40 (10 ± 0) | 50 (10 ± 0) | N.S. | 50 (10 ± 0) | N.S. |
Gametocyte | 65 (16.25 ± 4.27) | 44 (8.8 ± 6.46) | * | ▽ | 29 (5.8 ± 4.67) | ** | ▽ |
- Counts for each blood stage were compared between wild type (WT) (n = 4) and Plasmodium berghei (Pb) breast cancer susceptibility protein 2 (PbBrca2)-knockout 1 (KO1) (n = 5) or -KO2 (n = 5) parasite-infected mice. Numbers in parentheses indicate the mean ± SD. Black triangles indicate a significant increase in the count at that stage compared to that of WT, white triangles indicate a significant decrease in the count at that stage compared to that of WT. * P < 0.05, ** P < 0.01, N.S. non-significant (vs. WT parasites, compared using χ2-test)