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Table 4 Diagnostic value of the different parameters or combined markers for predicting liver fibrosis in patients infected with Schistosoma japonicum

From: Association between serum lipid profile and liver fibrosis in patients infected with Schistosoma japonicum

 

AUC (95% CI)

Cut-off point

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

P

HDL

0.675 (0.648–0.701)

1.41

60.5

67.4

65.7

62.2

 < 0.001

LDL

0.683 (0.657–0.710)

3.55

74.0

50.7

65.3

60.8

 < 0.001

HB

0.648 (0.621–0.676)

134

66.8

54.3

61.2

60.1

 < 0.001

PLT

0.604 (0.575–0.632)

131

32.7

84.4

54.8

68.5

 < 0.001

FIB-4

0.624 (0.596–0.653)

2.20

46.1

74.3

65.3

57.0

 < 0.001

APRI

0.608 (0.580–0.636)

0.49

33.8

83.4

67.8

54.9

 < 0.001

(HDL × 100)/(LDL × HB)

0.773 (0.750–0.796)

0.33

62.3

77.4

74.0

66.5

 < 0.001

  1. AUC Area under receiver operating characteristic curve, PPV positive predictive value, NPV negative predictive value; for other abbreviations, see Tables 1, 2 and 3