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Table 2 Frequency of D. immitis-positive cases by individual and parallel diagnostic methods (n = 300)

From: Probe-based qPCR as an alternative to modified Knott’s test when screening dogs for heartworm (Dirofilaria immitis) infection in combination with antigen detection tests

Diagnostic method(s)

D. immitis-positive dogs (n)

Frequency % (95% CI)

MK

55

18.3 (14.4–23.1)

qPCR

62

20.7 (16.5–25.6)

DiroCHEK® pre-ICD

74

24.7 (20.1–29.8)

DiroCHEK® post-ICD

88

29.3 (24.5–34.7)

MK + DiroCHEK® pre-ICD

75

25.9 (20.4–30.2)

MK + DiroCHEK® post-ICD

88

29.3 (24.5–34.7)

qPCR + DiroCHEK® pre-ICD

77

25.7 (21.0–30.9)

qPCR + DiroCHEK® post-ICD

88

29.3 (24.5–34.7)

  1. MK modified Knott’s test; qPCR real-time PCR; ICD immune complex dissociation