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Fig. 5 | Parasites & Vectors

Fig. 5

From: MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection

Fig. 5

The miR-942-5p regulates TRAIL expression after C. parvum infection in HCT-8 cells. Cells were transfected with an miR-942-5p mimic or miR-942-5p inhibitor for 24 h. Cells were exposed to an equal number of C. parvum sporozoites for up to 48 h, followed by a western blot for TRAIL protein and real-time PCR analysis for TRAIL and caspase-8 mRNA. All data represent the combined mean ± SD of three independent experiments with two to three technical replicates per experiment. The data were analyzed with a one-way ANOVA followed by a Dunnett’s test for multiple comparisons. *P < 0.05; **P ≤ 0.01; ***P ≤ 0.001; ****P ≤ 0.0001

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Parasites & Vectors

ISSN: 1756-3305

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