Fig. 1

Toxoplasma gondii strains differ in their ability to activate the NF-κB promoter. a Toxoplasma gondii ME49s activate the NF-κB promoter. pNF-κB-Luc and pTL-TK plasmids were co-intransfected into HEK293T cells together with empty vector (blank) or infected with T. gondii ME49 at multiple MOIs. Eighteen hours post-infection, luciferase activity was measured. The relative luciferase activity was calculated by normalizing the fluorescence signals to the background. Error bars represent standard error. Data are presented as the average values of three independent experiments. b T.gHB1s activate the NF-κB promoter. c Toxoplasma gondii RHΔHX cannot activate the NF-κB promoter. (^*P < 0.05; ^****P < 0.0001; NS not significant)