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Table 1 List of genes isolated as GlMyb2 regulon by ChIP-sequencing

From: Identification of target genes regulated by encystation-induced transcription factor Myb2 using knockout mutagenesis in Giardia lamblia

Gene ID

Protein

Increase fold

Presence of promoter

Structural protein (6)

 GL50803_5435

Cyst wall protein 2

7.7

Yes

 GL50803_5638

Cyst wall protein 1

5.4

Yes

 GL50803_2421

Cyst wall protein 3

4.1

Yes

 GL50803_113531

High cysteine membrane protein EGF-like

5.3

Yes

 GL50803_114626

High cysteine membrane protein EGF-like

4.7

Yes

 GL50803_40376

High cysteine non-variant cyst protein

3.7

Yes

Transcription factor (1)

 GL50803_8722

Myb 1-like protein

5.9, 4.8

Yes

Stress response (1)

 GL50803_2556

ATP-dependent Clp protease ATP-binding subunit ClpB

4.5

No

Signaling pathway (7)

 GL50803_137701

Kinase, NEK

6.2

Yes

 GL50803_21924

Kinase, NEK

6.1

Yes

 GL50803_114495

Kinase, NEK

5.7

Yes

 GL50803_42657

Kinase, NEK

4.6

Yes

 GL50803_16862

Kinase, NEK

4.2

No

 GL50803_13109

RabA

3.1

Yes

 GL50803_7512

Protein tyrosine phosphatase-like protein

2.7

Yes

Transport (2)

 GL50803_6664

Zinc transporter domain

6.9

Yes

 GL50803_15469

SKD1 protein

3.1

Yes

Metabolism (8)

 GL50803_21118

Long chain fatty acid CoA ligase 5

3.6

No

 GL50803_112103

Arginine deiminase

3.6

Yes

 GL50803_14993

Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit

3.3

Yes

 GL50803_14651

Glucosamine 6-phosphate N-acetyltransferase

2.7

Yes

 GL50803_113021

Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative

2.6

Yes

 GL50803_137673

Reverse transcriptase/endonuclease,

putative

2.2, 1.9, 1.7, 1.6

No

 GL50803_r0021

28S ribosomal RNA

1.8, 1.6

No

 GL50803_r0018

5.8S ribosomal RNA

1.7

No

Unknown function (1)

 GL50803_7875

Parkin co-regulated gene

3.0

Yes

Hypothetical protein (18)

 GL50803_115669

Hypothetical protein

5.9

No

 GL50803_7107

Hypothetical protein

5.4, 4.0

No

 GL50803_846

Hypothetical protein

5.2

No

 GL50803_98653

Hypothetical protein

4.5

No

 GL50803_14164

Hypothetical protein

4.3, 3.9

No

 GL50803_21048

Hypothetical protein

4.2

Yes

 GL50803_27724

Hypothetical protein

4.1

No

 GL50803_105798

Hypothetical protein

4.0

No

 GL50803_112008

Hypothetical protein

3.8

No

 GL50803_39607

Hypothetical protein

3.6

No

 GL50803_16078

Hypothetical protein

3.6

Yes

 GL50803_105640

Hypothetical protein

3.1

No

 GL50803_113285

Hypothetical protein

3.1

No

 GL50803_98638

Hypothetical protein

3.0

No

 GL50803_2926

Hypothetical protein

3.0

Yes

 GL50803_36117

Hypothetical protein

2.9

No

 GL50803_16731

Hypothetical protein

1.9

No

 GL50803_135294

Hypothetical protein

1.6

No