Fig. 4

Biliary fibrosis in the IL-33 WT and IL-33 KO mice infected by Clonorchis sinensis. A–B Depositions of extracellular matrix as indicated by Masson’s staining and further semi-quantified by percent of blue area in the hepatic section of mice from all groups (n = 4–5). C–D IHC staining of α-SMA in livers of the mice from all groups; the sections were quantified by integral optical density using Image J software (n = 5). (E) Hydroxyproline content (n = 5). The values were expressed as mean ± SEM. Compared with indicated groups, *P < 0.05, ***P < 0.001; ns not significant. All data represent at least three independent experiments