Genetic diversity in the transmission-blocking vaccine candidate Plasmodium vivax gametocyte protein Pvs230 from the China–Myanmar border area and central Myanmar

Table 2 Genetic diversity of Pvs230 among global isolates

Region	Country	n	S	η	k	π ± SD	NS	SP	H	Hd ± SD	GenBank accession numbers
East Asia	China–Myanmar	143	30	31	5.558	0.002 ± 0.000	22	9	47	0.935 ± 0.009
East Asia	Central China	20	14	14	3.711	0.001 ± 0.000	12	2	11	0.911 ± 0.042	AB574574–AB574555
Southeast Asia	Myanmar	23	19	20	3.553	0.001 ± 0.000	17	3	15	0.925 ± 0.042
Southeast Asia	Thailand	20	19	20	4.411	0.002 ± 0.000	16	4	15	0.968 ± 0.025	AB574575–AB574594
West Asia	Turkey	20	6	7	1.774	0.001 ± 0.000	5	2	5	0.511 ± 0.128	AB574528–AB574547
Africa	Madagascar	7	7	7	2.762	0.001 ± 0.000	5	2	6	0.952 ± 0.096	AB574548–AB574554
South America	Brazil	20	8	8	3.079	0.001 ± 0.000	6	2	6	0.768 ± 0.062	AB574508–AB574527
Oceania	PNG	21	12	12	2.248	0.001 ± 0.000	9	3	9	0.767 ± 0.090	AB574595–AB574615
	Total	274	46	48	5.541	0.002 ± 0.000	32	16	92	0.968 ± 0.004

n, number of isolates; S, number of polymorphic (segregating) sites; η, the total number of mutations; k, the average number of nucleotide differences; π, nucleotide diversity; NS, number of sites with non-synonymous polymorphisms; SP, number of sites with synonymous polymorphisms; H, number of haplotypes; Hd, haplotype diversity; SD, standard deviation; PNG, Papua New Guinea population

ISSN: 1756-3305