Table 1 The frequency of kdr mutations (S989P + V1016G and F1534C) in Aedes aegypti from Saudi Arabia compared with Southeast Asia
Domain | Codon | Nucleotide | AA | Designation | Saudi Arabia | Southeast Asia | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Jazan (n = 71) | Sahil (n = 26) | Jeddah (n = 36) | Makkah (n = 28) | Madinah (n = 32) | Thailand (n = 40) | Myanmar (n = 24) | |||||
IIS6 | 989–1016 | TCC/TCC-GTA/GTA | S/S-V/V | Homozygous wild type | 39 | 13 | 9 | 8 | 12 | 17 | 20 |
989–1016 | TCC/CCC-GTA/GGA | S/P–V/G | Heterozygous | 23 | 12 | 8 | 12 | 12 | 16 | 2 | |
989–1016 | CCC/CCC-GGA/GGA | P/P-G/G | Homozygous mutant | 9 | 1 | 19 | 8 | 8 | 7 | 2 | |
|  |  |  | Frequency of kdr allele (95% CI) | 0.29 (0.139—0.343) | 0.28 (0.124—0.480) | 0.49 (0.462—0.787) | 0.50 (0.311—0.689) | 0.44 (0.268—0.621) | 0.38 (0.232—0.542) | 0.23 (0.033—0.335) | |
IIIS6 | 1534 | TTC/TTC | F/F | Homozygous wild type | 9 | 6 | 6 | 6 | 8 | 9 | 16 |
1534 | TTC/TGC | F/C | Heterozygous | 35 | 8 | 21 | 14 | 12 | 17 | 7 | |
1534 | TGC/TGC | C/C | Homozygous mutant | 27 | 12 | 9 | 8 | 12 | 14 | 1 | |
|  |  |  | Frequency of kdr allele (95% CI) | 0.63 (0.441—0.679) | 0.63 (0.407—0.790) | 0.54 (0.370—0.705) | 0.54 (0.342—0.711) | 0.56 (0.379—0.731) | 0.56 (0.398—0.715) | 0.19 (0.066—0.404) | |