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Table 1 Hemato-biochemical profiles from the first check-up (1 week before the surgery) to the recovery of the Hepatozoon-infected cat

From: First autochthonous clinical case of Hepatozoon silvestris in a domestic cat in Italy with unusual presentation

 

Reference ranges

Days

− 7

0

 + 4

 + 13

Blood count

RBC

7.1–11.5 M/µl

6.9

7.0

5.3

5.0

Hct

28.2–52.7%

30.4

28.8

20.9

19.5

Hb

10.3–16.2 g/dl

10.8

10.3

7.9

7.3

MCV

39–56 fl

44.4

41.4

39.3

39.3

MCH

12.6–16.5 pg

15.8

14.8

14.8

14.7

MCHC

28.5–37.8 g/dl

35.5

35.8

37.8

37.4

Reticulocytes (total count)

K/µl

115.1

25

10.1

32.2

WBC

3.9–19 K/µl

15.7

20

15.6

14.2

Neutrophils (total count)

2.62–15.17 K/µl

13.368

14.763

13.706

12.581

Band neutrophils (total count)

0–300/µl

0

2195

0

0

Lymphocytes (total count)

0.85–5.85 K/µl

1.443

1.795

0.749

0.895

Monocytes (total count)

0.04–0.53 K/µl

0.706

1.197

1.124

0.653

Eosinophils (total count)

0.09–2.18 K/µl

0.157

0

0.03

0.07

Basophils (total count)

0–0.1 K/µl

0

0

0

0

PLT

155–641 K/µl

259

266

211

183

Notes

  

Rouleaux (+++)

Burr cells (++)

Anisocytosis (+)

Hepatozoon gamont in neutrophils

Platelet aggregates

Rouleaux (+)

Heinz bodies (+)

Doehle bodies

Neutrophils: foamy (+) and basophilic (++) cytoplasm

Rouleaux (+)

Platelet aggregates

Instrument: Sysmex XT2000iV, Sysmex, Kobe, Japan

Biochemical profile

Glucose

63–140 mg/dl

85

80

84

97

SDMA

0–14 µg/dl

12

12

19

11

Creatinine

0.9–2.3 mg/dl

1.5

1.6

1.0

0.8

BUN

16–38 mg/dl

23

67

31

18

Phosphates

2.48–6.81 mg/dl

4.34

5.26

4.02

4.02

Calcium

8.82–11.62 mg/dl

8.82

8.42

8.0

8.82

Magnesium

1.46–2.67 mg/dl

2.19

3.4a

2.19

1.7

Sodium

147–159 mmol/l

149

140

149

154

Potassium

3.3–5.8 mmol/l

4.8

4.8

5.0

4.5

Chloride

109–129 mmol/l

115

94

116

122

Total protein

5.9–8.7 g/dl

6.2

6.7

5.8

6.8

Albumin

2.7–4.4 g/dl

2.4

2.5

1.9

2.2

Globulins

2.9–5.4 g/dl

3.8

4.2

3.9

4.6

Albumin/globulins

 > 0.57

0.64

0.60

0.48

0.49

ALT

27–175 U/l

38

31

51

34

AST

14–71 U/l

29

83

49

26

ALP

12–73 U/l

35

23

60

37

GGT

0–5 U/l

 < 1

2

 < 1

 < 1

Bilirubin (total)

0–0.4 mg/dl

0.2

 < 0.1

0.3

0.2

Cholesterol

86–329 mg/dl

123

196

199

149

Triglycerides

21–432 mg/dl

33

60

45

34

Lipase

0.1–45 U/l

nd

21

nd

14

CPK

52–542 U/l

111

2371

1156

313

Urinary creatinine

mg/dl

373

224

nd

nd

Urinary total protein

mg/dl

61.6

42.4

nd

nd

PU/CU

 < 0.33

0.2

0.2

nd

nd

Fructosamine

137–286 µmol/l

148

305

150

150

General notes

  

Vomiting, anorexia, stress, severe depression

 

Good general conditions

Instrument: Beckman-Coulter, Brea, CA, USA

  1. RBC red blood cell count, Hct hematocrit, Hb hemoglobin, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, WBC white blood cell count, PLT platelet count, SDMA symmetric dimethylarginine, BUN blood urea nitrogen, ALT alanine transferase, AST aspartate transferase, ALP alkaline phosphatase, GGT gamma-glutamyl transferase, CPK creatine phosphokinase, PU/CU urine protein to creatinine ratio, nd Not done
  2. aHemolytic serum