Fig. 1
From: Characterization of glutamate carboxypeptidase 2 orthologs in trematodes
Sequence alignment of SmM28B, FhM28B, and HsGCP2. The intracellular part and the transmembrane domain of human GCP2 are shaded gray and magenta, respectively. Protease-like (blue), apical (yellow), and C-terminal dimerization (red) domains are present. The catalytic acid/base glutamate is highlighted by the green background in the rectangular box. Residues coordinating zinc ions are marked by red rectangular boxes, and residues coordinating α-carboxylate binding are shaded in the violet background in rectangular boxes