Table 1 Studies included in the review
From: Protocols for Plasmodium gametocyte production in vitro: an integrative review and analysis
Year of publication | First author | Title | Journal | References |
|---|---|---|---|---|
2007 | Fivelman | Improved synchronous production of Plasmodium falciparum gametocytes in vitro | Mol Biochem Parasitol. 154:119–23 | [54] |
2011 | Buchholz | A high-throughput screen targeting malaria transmission stages opens new avenues for drug development | J Infect Dis. 203:1445–53 | [29] |
2012 | Lelièvre | Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence ‘‘Transmission Blocking’’ Assay | PLoS One. 7:e35019 | [39] |
2012 | Roncalés | Comparison and optimization of different methods for the in vitro production of Plasmodium falciparum gametocytes | J Parasitol Res. 2012:927148 | [32] |
2013 | Saliba | Production of Plasmodium falciparum gametocytes in vitro | Method Mol Biol. 923:17–25 | [48] |
2015 | Brancucci | An assay to probe Plasmodium falciparum growth, transmission stage formation and early gametocyte development | Nat Protoc. 10:1131–42 | [41] |
2015 | Reader | Nowhere to hide interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination | Malar J. 14:213 | [31] |
2015 | Vera | Purification methodology for viable and infective Plasmodium vivax gametocytes that is compatible with transmission-blocking assays | Antimicrob Agents Chemother. 59:6638–41 | [51] |
2016 | Delvesl | Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions | Nature Protocols. 11:1668–80 | [37] |
2016 | Duffy | Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery | Nat Protoc. 11:976–92 | [43] |
2017 | Demanga | The development of sexual stage malaria gametocytes in a wave bioreactor | Parasit Vectors. 10:216 | [38] |
2018 | Armisteadl | Infection of mosquitoes from in vitro cultivated Plasmodium knowlesi H strain | Int J Parasitol. 48:601–10 | [47] |
2018 | Pathak | Cryogenically preserved RBCs support gametocytogenesis of Plasmodium falciparum in vitro and gametogenesis in mosquitoes | Malar J. 17:457 | [68] |
2018 | Rangel | Enhanced ex vivo Plasmodium vivax intraerythrocytic enrichment and maturation for rapid and sensitive parasite growth assays | Antimicrob Agents Chemother. 62:e02519-17 | [52] |
2019 | Tanakal | Polyunsaturated fatty acids promote Plasmodium falciparum gametocytogenesis | Biol Open. 8:bio042259 | [55] |
2020 | Portugaliza | Artemisinin exposure at the ring or trophozoite stage impacts Plasmodium falciparum sexual conversion differently | Elife. 9: e60058 | [42] |
2020 | West | Lactic acid supplementation increases quantity and quality of gametocytes in Plasmodium falciparum culture | Infect Immun. 89: e00635-20 | [50] |
2020 | Llorà-Batlle | Conditional expression of PfAP2-G for controlled massive sexual conversion in Plasmodium falciparum | Sci Adv. 6:eaaz5057 | [46] |
2021 | Wadi | Investigation of factors affecting the production of P. falciparum gametocytes in an Indian isolate | 3 Biotech. 11:55 | [30] |
2021 | Boltryk | CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research | Nat Commun. 12:4806 | [45] |
2021 | Ridgway | Sex-specific separation of Plasmodium falciparum gametocyte populations | Bio Protoc. 11:e4045 | [44] |
2022 | Ramos | Viability and infectivity of Plasmodium vivax gametocytes in short-term culture | Front Cell Infect Microbiol. 11:676276 | [53] |
2022 | Dinko | Generation of Plasmodium falciparum gametocytes in vitro with specific consideration for field isolates | Method Mol Biol. 2470:121–32 | [40] |