Fig. 5
From: Aedes aegypti Malpighian tubules are immunologically activated following systemic Toll activation
Comparison of Malpighian tubule transcriptomic and hemolymph proteomic responses following Toll activation. a GSEA was performed on the Malpighian tubule RNA sequencing using a gene set consisting of proteins that were significantly upregulated in the hemolymph proteomics. The y-axis shows the ES, and the x-axis shows the log2FC rank of all genes detected in the Malpighian tubule transcriptome. Black ticks represent where proteins in the hemolymph-upregulated proteome gene list fall on the continuum of ranked genes. ES and the corrected P-value (FDR) for this analysis are shown. b Among the 168 genes that were significantly upregulated only in the Malpighian tubules upon dsCactus treatment, 39 were also upregulated in the hemolymph proteome