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Fig. 3 | Parasites & Vectors

Fig. 3

From: Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice

Fig. 3

The effect of TGF-β1/Smad signaling in S. japonicum-infected mice. a The expression of the transcript of TGF-β1, Smad2/3, Smad4, and d Smad7 in primary HSCs at different time points was determined by RT-qPCR. b The expression of the protein of TGF-β1, Smad2/3, Smad4, and e Smad7 was detected by Western blot, c, f, and the densitometric analysis was normalized to the level of β-actin in primary HSCs. Data are presented as mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, compared with the 0 wpi group

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