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Fig. 4 | Parasites & Vectors

Fig. 4

From: Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice

Fig. 4

miRNA target prediction and the expression of miRNAs in primary HSCs of S. japonicum-infected mice at 0, 4, 7, and 9 weeks. a Bioinformatics analysis as predicted by TargetScan and miRanda showed that the 3′-UTR of Smad7 contained the binding site of miRNA-21, and the 3′-UTR of Smad4. b The relative expression levels of miRNA-21 and miRNA-454 were determined by RT-qPCR. Data are presented as mean ± SD (n = 3). *P < 0.01; ***P < 0.001, compared with the 0 wpi group

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Parasites & Vectors

ISSN: 1756-3305

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