Fig. 2
From: Effects of different drugs and hormone treatment on Toxoplasma gondii glutathione S-transferase 2
The influence of progesterone and estradiol on the enzyme activity and localization of TgGST2. A The significant decrease in enzymatic activity of rTgGST2 after progesterone and estradiol treatment, and the inhibitory effect is enhanced with increasing hormone concentration. B Localization of TgGST2 treated with P4 and E2, using DMSO as control. Under 10–5 M P4 treatment, the Golgi-located TgGST2 disappeared and vesicle-TgGST2 became vacuolated; under overexposure to 10–6 M of P4, vesicle-TgGST2 was vacuolated, Golgi-localized TgGST2 was only observed; otherwise, the same as the control group. HA (green), anti-mouse antibody; GAP45 (red), anti-rabbit antibody; Hoechst (blue); scale bar, 2 μm