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Fig. 2 | Parasites & Vectors

Fig. 2

From: Capsaicin decreases fecundity in the Asian malaria vector Anopheles stephensi by inhibiting the target of rapamycin signaling pathway

Fig. 2

The TOR signaling pathway was significantly inhibited by blood feeding on CAP-treated mice. A The transcription levels of the key fecundity-related genes (AsAkt, AsTOR, AsS6K, and AsVg) were significantly lower in the CAP group than in the control group. B The western blot results showed that the phosphorylated AKT (p-AKT), TOR (p-TOR), and S6K (p-S6K) levels and Vg protein levels relative to the reference protein β-Actin were obviously downregulated by CAP pretreatment. This indicates that CAP inhibited the TOR signaling pathway. Data analysis was confirmed by t-test. *P < 0.05; **P < 0.01; ***P < 0.001; ns, no significant difference

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